Molecular Epidemiology of Hepatitis B Virus

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Molecular Epidemiology of Hepatitis B Virus

Although safe and effective vaccines for hepatitis B virus (HBV) have been available for nearly three decades, this virus kills at least 600,000 people annually worldwide and remains the leading global cause of chronic hepatitis, cirrhosis, and hepatocellular carcinoma. Because the HBV reverse transcriptase lacks a proofreading function, many HBV genotypes, subgenotypes, mutants, and recombinan...

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Molecular epidemiology of Hepatitis B virus genotypes in Pakistan

BACKGROUND Eight genotypes of Hepatitis B virus designated A-H, have been known but in Pakistan, no such data is available on the prevalent HBV genotypes. Therefore, the subject study was conducted to determine HBV genotypes in the indigenous Pakistani population. METHODS A total of 690 individuals were enrolled for HBV screening with EIA and nested PCR. Positive samples were further analyzed...

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Molecular epidemiology of gibbon hepatitis B virus transmission.

Although transmission of human hepatitis B virus (HBV) variants to nonhuman primates is well documented, it remains to be elucidated whether nonhuman primate HBV is transmissible to humans. The prevalence and transmission routes of gibbon HBV were analysed in 101 captive gibbons in Thailand. Approximately 40 % of these animals showed at least one marker of HBV infection; 19 animals were chronic...

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Molecular epidemiology of hepatitis B virus isolated from Bangladesh

BACKGROUND Hepatitis B virus (HBV) is highly contagious and causes liver diseases. Globally more than 350 million people are chronically infected and among them above 80 % are from developing countries like Bangladesh. Resistance to existing drugs and vaccines are common phenomenon due to mutations in HBsAg 'a' determinant. Due to lack of data about mutations and subtypes of HBV in Bangladesh, ...

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Epidemiology of Hepatitis B virus (HBV) Infection and its Prevalence in Rafsanjan

Background and Aims: Chronic hepatitis B virus (HBV) infection is one of the most important health problems worldwide. Currently, Iran is located in the intermediate HBV zone,This study was conducted to find out the prevalence of HBV  infection among patients referring the hospital care in Rafsanjan, Iran. Materials and Methods: A total of 2030 blood samples (471from  males and 1559 ...

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ژورنال

عنوان ژورنال: The Korean Journal of Internal Medicine

سال: 2011

ISSN: 1226-3303

DOI: 10.3904/kjim.2011.26.3.255